Structure ELSPAC database

ELSPAC database

elspac logo

This most recently established newest core facility aims to bridge the gap between environmental and health data, and between ecological and human risk assessment. It has been generally accepted that the majority of chronic human diseases result from the combination of genetics and environmental exposures to chemical and physical stressors. Environmental determinants and the mechanisms of their contribution, however, are poorly understood. In order to improve our understanding of triggering mechanisms of environmentally-induced diseases, we must analyze data from long-term epidemiological and environmental studies.

ELSPAC (European Longitudinal Study of Pregnancy and Childhood) is a prospective longitudinal study initiated by WHO (World Health Organisation; European Offi ce in Copenhagen). It has been performed in several European countries by monitoring selected population samples of children and their families from the pregnancy of the mother to at least 19 years of the adolescent´s age. A database containing results of the Czech cohort allows investigation of individual factors (genetics, environment, life style, stress) as well as their combinations for possible association with population health.

Reasearch areas using ELSPAC database

  • The ELSPAC database cohort can be used as a control group for a number of medical analyses.
  • Due to its territorial character, the ELSPAC study extensively monitors the Brno region and provides data on inhabitants’ migration or children’s fluctuation between education facilities in the region
  • Due to the duration of the ELSPAC study, it can be used as a basis to investigate the impact of the political and social transition from a communist to democratic regime and market economy on human health and quality of life.
  • Family environment has been extensively monitored in the ELSPAC database, which can serve as a starting point to investigate effects of the family on later successes and failures of young people.
  • Based on a detailed family medical history, health status of the investigated cohort can be assessed from the viewpoint of congenital and acquired health risks.
  • Records of school results and behaviour of children can bring new insight to education issues with a comprehensive view on the child in the context of his/her health status and family environment.
  • Development of a comprehensive on-line browser and reporting system working with the database of the Czech ELSPAC cohort.

Contact person

Lenka Andrýsková, Ph.D.
Phone: +420 549 493 079