The development of periodontitis is influenced by genetic factors, but the most common trigger is the long‑term accumulation of dental plaque around the gums and between the teeth, where bacteria build up. When they overgrow, they cause gum inflammation, which can gradually spread into deeper tissues. In addition to insufficient oral hygiene, other factors also contribute to the progression of periodontitis, such as smoking, illnesses, stress, weakened immunity, or hormonal changes.
‘Inflammatory dental diseases most often begin to appear between the ages of 35 and 45. If their onset is not detected in time, the disease progresses silently and can eventually lead to tooth loss in later life,’ explains Filip Hromčík, periodontologist and researcher at St. Anne’s University Hospital in Brno. According to physicians, early‑stage periodontitis manifests less through gum recession and more through bleeding gums, bad breath, or bone loss.
A team of Czech scientists and researchers has become the first in the world to develop a dental nanofloss containing beneficial probiotic cultures capable of suppressing bacteria that cause gum inflammation. No other dental nanofloss — and not even a conventional dental floss enriched with probiotics — exists anywhere else in the world.
Sabina Cerulová originally planned to study veterinary medicine, but coincidence, the covid‑19 pandemic, and her bachelor’s project led her to research at RECETOX. Today, she studies a rare genetic mutation responsible for severe symptoms in a specific patient, and she works with animal models, microbiome, and advanced imaging methods.
Reducing the incidence of chronic diseases is the goal of a newly established European Exposome Alliance of the European Parliament. RECETOX has also played a significant role in its establishment.
