|Project title:||Linking chemical perturbations of chitin synthesis to developmental disorders in crustaceans|
To establish and evaluate the AOP “Chitin synthesis inhibitors leading to developmental disorders and death in freshwater crustaceans”.
Conceptual AOP developed and evaluated, submitted to the AOP-wiki and knowledge gaps identified to guide experimental studies.
||VUA, M15, 1 month, histochemistry, histopathology and in situ hybridisation in D. magna
CSIC-CEAB, M20, 2 months, multispecies exposures
EI, M30, 1 month – chemical analysis and data-mining of demonstration studies from WP5 (JDS4)
|Work packages:||3 - Linking molecular responses to effects at higher biological levels using adverse outcome pathways (AOPs)
5 - Risk assessment and socio-economic evaluation of ecological effects
|Supervisor:||Knut Erik Tollefsen, NIVA|
|Host institution:||Norwegian Institute for Water Research|
|Enrolment:||Norwegian University of Life Sciences|