|Project title:||Linking phenotype, developmental and behavioral outcomes to metabolomic pathways in aquatic snails and terrestrial arthropods|
To develop a combined in vivo and in vitro metabolomic approach to investigate molecular mechanisms and pathways of neonicotinoid toxicity.
New insights into molecular mechanisms and pathways of neonicotinoid toxicity. In vitro and combined cross-omic strategy (metabolomics, proteomics and genomics; collaboration with ESR5) to confirm MoA and toxicity mechanism associated with the AOP.
||MU, M22, 2 months, in vitro studies
RIWA, M26, 2 months, data analysis
|Work packages:||3 - Linking molecular responses to effects at higher biological levels using adverse outcome pathways (AOPs)
4 - Predicting effects on ecosystem services through AOPs
|Host institution and enrolment:||Vrije Universiteit Amsterdam|