|Project title:||Linking retinoid and thyroid hormone signaling disruption with adverse effects on early development|
Characterize the relation of endocrine disruption via interference with retinoid and thyroid hormone signaling with adverse effects of pollutants on early development of fish.
Assessment of early developmental effects in aquatic vertebrates (fish) with key role of retinoid and thyroid hormone signaling; their increased occurrence leads to adverse outcomes to structure (ageing) and growth of populations.
|Place:||Brno, Czech Republic|
||VUA, M17, 2 months – development and optimization of the methods for metabolomics and biomarker analyses
Du Pont, M27, 2 months – methodologies of bioanalyses and metabolomics in industry
|Work packages:||3 - Linking molecular responses to effects at higher biological levels using adverse outcome pathways (AOPs)
4 - Predicting effects on ecosystem services through AOPs
|Supervisor:||Klara Hilscherova, MU|
|Host institution and enrolment:||Masaryk University|