Mgr. David Bednář, Ph.D.
Molecular modelling and bioinformatics
David Bednář is a leader of a group focused on molecular modelling and bioinformatics within Loschmidt's laboratories at the Faculty of Science of Masaryk University. He received his doctoral degree in 2017 from the same university, studying the field of Molecular and Celluar Biology. His expertise was further extended during internships abroad at Rutgers University (USA), University of North Carolina (USA), and Adam Mickiewicz University (Poland). Currently, he teaches the Structural Biology course at Masaryk University and also contributes to the courses Protein Engineering and Methods of Biophysical Chemistry.
David is a co-author of 33 publications in impacted scientific journals (h-index 11), a book chapter and an international patent. He participated in the development of 9 bioinformatics tools for enzyme analysis and protein engineering and one bioinformatics database. In his work, he applies in silico approaches to understand basic principles of enzymology and design of mutations to improve protein properties. In recent years, he has been involved also in medical projects covering the study and treatment of Alzheimer's disease, stroke or cancer. The knowledge obtained in both enzymological and medical projects is further utilized in the development of the bioinformatics tools, which bring these analyzes to the broader scientific community.