Biostatistics and Bioinformatics in Exposomics

From genomics to metabolomics and from epigenomics to biomedical imaging, this core facility offers integrated data analysis and tailored solutions in bioinformatics, biostatistics and biomarker discovery following the experimental life cycle.

The recently established core facility is dedicated to analyzing big data from various fields of life sciences. We have extensive experience in data analysis from various *omics modalities and bioimaging. The facility focuses on applied data analysis and method development. We provide complex integrative data mining and statistical analysis of data from omics experiments, including result interpretation. In addition, we offer data-driven hypothesis generation. We are specialized in biomarker detection and construction of predictive, prognostic or diagnostic signatures and classifiers. The group also develops its own portfolio of methods and customized data analysis pipelines to answer various less standard analytical problems.

Services

The facility provides following services:

Analyses / Access to Data

  • Complex integrative data mining and statistical analysis of data from omics experiments, including result interpretation and hypothesis generation;
  • Biomarker detection, construction of predictive, prognostic or diagnostic signatures and classifiers;
  • Omics data we are able to handle from raw files (pre-processing, normalization...) to final interpretation of results:
    • untargeted LC-MS and GC-MS data from metabolomic, proteomic and small compound analysis experiments,
    • genomic, transcriptomics, epigenomics, ...data from microarrays and NGS,
    • targeted and untargeted metagenomic data of microbiome studies;
  • Image analysis and feature detection of histopathological slides.

Consultations

Whether you are just thinking about a new experiment or already have the resulting data, you may contact us with your questions and we will assess the feasibility of the various analyses required. Ideally, you would contact us at the experimental design stage, so we can ensure that all the relevant information will be available to answer your questions.

We also provide consultations on data analysis and methods.

Access

The access to the RI services is available to both the academic and other, e.g. industrial, users. The users from academia may use the open-access project, while the users from the industry may contact RNDr. Petra Růžičková, Ph.D. directly to discuss available capacities and expertise.

Contact

For more or specific information, please, contact:

Mgr. Eva Budinská, Ph.D.

Head of the Biostatistics and Bioinformatics in Exposomics Facility

Phone: +420 549 49 3993
E‑mail:

Mgr. Eva Budinská, Ph.D.

Head, Integrative Bioinformatics and Biostatistics

Phone: +420 549 49 3993
E‑mail:

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