PharmDr. Zdeněk Spáčil, Ph.D.
Biomarkers of health and disease
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Dr. Zdeněk Spáčil holds a dual doctoral degree in analytical chemistry (2010) awarded from both Stockholm University, Faculty of Science (Sweden) and Charles University in Prague, Faculty of Pharmacy (Czech Republic). As a postdoctoral fellow (2010-2012) and later a research scientist (2014-2015) at the University of Washington, he worked under the tutelage of professors Tureček and Gelb. Currently, he is an assistant professor at Masaryk University, leading a newly established research group at the RECETOX Centre. He researches in the development of advanced analytics for metabolomics and targeted proteomics applied to functional characterization of microbiota, aging-induced metabolic and immunomodulatory modulations relevant to Alzheimer’s disease and pioneering the Exposome (i.e., non-genetic factors affecting human health).
He has expertise in instrumental analytical chemistry (i.e., mass spectrometry, separation science) and clinical chemistry. He substantially contributed to the National Institutes of Health NIH/NIDDK funded projects (Univ. of Washington, Seattle) and the Bill and Melinda Gates Foundation Grants (Institute for Systems Biology, Seattle). Currently, he is a principal investigator on several projects funded by the Czech Science Foundation (GACR project No. 17-24592Y), the Grant Agency of the Masaryk University (GAMU project No. MUNI/G/1131/2017) and the Czech Health Research Council (AZV project No. NV19-08-00472).
He published 29 research items in JCR-SCI journals with over 700 citations (excluding self-citations, h-index=15). He was leading author on 13 publications (9 first authorship; 6 corresponding authorship; 4 last authorship), and he also authored four patent applications.
He has extensive experience supervising Ph.D. students and postdoctoral fellows at the international level. He is currently a supervisor of five graduate students and a number of undergaduates.
Biomarkers of health and disease
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Chemico-Biological Interactions, year: 2024, volume: 397, edition: July 2024, DOI
Applied Microbiology and Biotechnology, year: 2024, volume: 108, edition: 1, DOI
Analytical chemistry, year: 2024, volume: 96, edition: 1, DOI
Year: 2023, type: Conference abstract
CELL REPORTS, year: 2023, volume: 42, edition: 11, DOI
MU Researcher: | prof. RNDr. Jana Klánová, Ph.D. |
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MU Faculty or unit: | Faculty of Science |
Project Period: |
1/2024 — 12/2024
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Investor: |
Masaryk University
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Specific research - support for student projects
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MU Researcher: | RNDr. Iva Sovadinová, Ph.D. |
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MU Faculty or unit: | Faculty of Science |
Project Period: |
1/2022 — 12/2024
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Investor: |
Czech Science Foundation
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Standard Projects
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MU Researcher: | prof. RNDr. Jana Klánová, Ph.D. |
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MU Faculty or unit: | Faculty of Science |
Project Period: |
1/2023 — 12/2023
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Investor: |
Masaryk University
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Specific research - support for student projects
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MU Researcher: | PharmDr. Zdeněk Spáčil, Ph.D. |
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MU Faculty or unit: | Faculty of Science |
Project Period: |
5/2019 — 12/2023
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Investor: |
Ministry of Health of the CR
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Ministry of Health Research Programme 2015 - 2022
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MU Researcher: | prof. RNDr. Jana Klánová, Ph.D. |
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MU Faculty or unit: | Faculty of Science |
Project Period: |
11/2015 — 6/2023
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Investor: |
Ministry of Education, Youth and Sports of the CR
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Operational Programme Research, Development and Education
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