The CELSPAC Biobank is an open-access infrastructure that collects, processes, stores, and subsequently distributes various types of biological samples (e.g. cord blood, blood, milk, urine) derived from population, environmental, bio-monitoring and clinical studies. The samples are used for basic scientific research and for development of new diagnostic methods. Presently, our infrastructure primarily handles biological material collected in the CELSPAC population studies. In combination with the survey data, these samples contain invaluable information, offering local, as well as international researchers, vast amounts of information.
To reduce the risk of procedural errors, a large proportion of blood and urine samples are automatically processed by equipment capable of recognizing individual blood fractions and subsequently stored in a fully automatic storage system. Individual aliquots can be stored for many years at temperatures of -25°C, -80°C, or -150 °C. Furthermore, the facility’s environment (e.g. humidity and temperature) are tightly monitored and controlled; systems requiring electrical energy for cooling samples are backed up by secondary refrigerant sources. This ensures precision, repeatability, and prevention of sample contamination or degradation.
Maintaining the highest level of data protection is guaranteed by the laboratory information system (LAS) which anonymously manages the large number of aliquots. The laboratory information system was developed in cooperation with the Czech national node of the European Biobanks Infrastructure Network (BBMRI) in order to ensure its compatibility with European standards.
The CELSPAC Biobank offer analyses of basic biomarkers of clinical chemistry and immunology in serum, plasma and urine along with the possibility of semi-automatic isolation of nucleic acids from whole blood or blood cells.
- Standard operating Procedures (SOPs) for collection, manual processing and long-term storage of biological sample aliquots
- Standard operating Procedures (SOPs) for collection, automatic processing and long-term storage of blood and urine aliquots
- Processing and storage of biological material for research projects according to validated SOPs
- Additional analysis of samples from ongoing studies
- Implementation of a laboratory information system
- Urine, serum and plasma biomarker analysis
We offer training in the following areas:
- Study planning and implementation, including biological sample collection, processing and storage
- Implementation of SOPs for the collection, processing, storage and distribution of various biological samples
- Data collection
We provide consultation in all types of services related to the biobanking facility.
Our epidemiological databases have been specifically designed to allow the sharing of data, in order to promote multidisciplinary research aimed at factors that can affect human health. Research proposals are assessed, and then selected for implementation by the CELSPAC Executive Board based on their quality and feasibility. The conditions of services provided are based on the contract concluded between the Faculty of Science of Masaryk University and the institution of the applicant.
For general information about accessing the infrastructure, please contact Petra Růžičková, Ph.D..
The CELSPAC ethics committee is the advisory body for the CELSPAC Executive Board and as such assesses ethical and legal issues pertaining to the use of the epidemiological databases, as well as ethical and legal issues related to the establishment of new Research Projects.
For more information, contact: