Environmental chemistry and modeling

The research program has long been focused on obtaining experimental data on the state and contamination of the environment, including its impact on humans, modeling the transport and distribution of environmental pollutants and their accumulation in living organisms, and predicting related risks. In line with the RECETOX research strategy, new approaches to the assessment of complex environmental exposures, including the study of human exposure (ie a set of factors that may negatively affect population health), are being developed in this program. 

The main objectives of the research are: 

  • developing innovative sampling and analytical techniques for multidisciplinary evaluation of complex mixtures of chemicals present in environmental and human tissue samples, including monitoring of their metabolites and biomarkers for their action in the body 
  • obtaining new data on exposure to environmental and biological organisms and levels of selected biomarkers 
  • studying sources and emissions, modeling of distribution and behavior of toxic substances in the environment and organisms and related health risks 
  • providing comprehensive data for new legislation, responsible management of chemicals and reducing health risks. 

The aim of the research is not only to identify the substances and chemical mixtures to which the population is exposed, but also to identify their sources and exposure routes, as well as the most vulnerable population groups to be protected when developing new chemical management measures. Innovative sampling and analytical methods are used to measure contamination of environmental samples, biological samples and human tissues to identify actual exposure patterns. 

Data on the presence of specific chemicals mixtures indoor and outdoor air, dust, water, food and products are combined with data on contamination of bodily fluids and tissues of selected population groups and information on their lifestyle and health. Particular emphasis is placed on examining differences in exposure patterns in relation to socio-demographic, behavioral and health characteristics. The use of state-of-the-art models makes it possible to estimate the actual exposure of different population groups and the chemical risks, thus encouraging the adoption of new measures for the safe management and protection of human health from their effects. 

prof. RNDr. Jana Klánová, Ph.D.

Research programme coordinator


Phone: +420 549 49 1477
E‑mail:

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